Core Nutritionals 5-AT
SKU: 19773956515

Core Nutritionals 5-AT

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Description

Core Nutritionals 5-AT5 Etioallocholen 3b,7b,17b triol: More commonly known as androstenetriol, 5 etioallocholen 3 beta 7 beta 17beta triol is a metabolite of the ubiquitous endogenous steroid, dehydroepiandrosterone (DHEA). DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions include, though are not limited to, serving as an intermediate (a middle piece) in the synthesis of sex

5-Etioallocholen-3b,7b,17b-triol: More commonly known as androstenetriol, 5-etioallocholen-3 beta-7 beta-17beta-triol is a metabolite of the ubiquitous endogenous steroid, dehydroepiandrosterone (DHEA). DHEA is one of the most abundant endogenous steroids in the human body, playing a critical role in a number of bodily functions. These functions include, though are not limited to, serving as an intermediate (a middle piece) in the synthesis of sex steroids such as testosterone and estrogen, up-regulating (increasing) immune response and countering the immunosuppressive actions of corticosteroids, and maybe the most impressive, directly and strongly suppressing the release of cortisol itself!

Though DHEA’s properties have been well-established and understood for decades, derivatives and metabolites of DHEA have more recently been the subject of research in animals and humans – demonstrating effects that are, at times, many orders of magnitude more significant than the parent compound (up to 100x as potent!).

Like DHEA, cortisol is one of the body’s most abundant and important endogenous steroids. While detailing in full the expansive list of cortisol’s functions is impossible, we can generally say that cortisol’s role in the human body is to break down bodily tissue and nutrients for the purpose of energy provision (to be catabolic), to act as an immunosuppressive, and to regulate blood sugar. Cortisol fulfills these functions by inducing gluconeogenesis (the breakdown of non-glucose intermediates, such as amino acids in muscle tissue, into glucose) and glycogenolysis (the breakdown of glycogen into glucose), inhibiting peripheral glucose utilization, and inhibiting cell lines critical to the body’s immune response.

In less complex terms, we can simply say that cortisol is responsible for inhibiting many of the processes that we as fitness enthusiasts want to start, and for starting many of the processes that we want to inhibit. Cortisol plays a role in:

1. Preventing our muscle cells from uptaking glucose (inducing insulin resistance).
2. Preventing muscle protein synthesis.
3. The breakdown of glycogen (the compound responsible for that “full look”).
4. Suppressing the immune processes involved in muscle growth.

While these are necessary functions, their overexpression is precisely the opposite of what we want – in fact, certain trials in humans have shown that an increase in plasma cortisol within the physiologic range increases proteolysis (breakdown of proteins) and degrades whole body amino acid synthesis! That is bad, bad news.

Enter DHEA and its metabolite, androstenetriol: In emerging animal literature, both androstenetriol and its metabolites have been shown to possess very potent anti-glucocorticoid activity – remembering that cortisol is the parent compound for this group – and anti-immunosuppressive actions in a number of different tissue types. In fact, androstenetriol is one of the most potent anti-glucocorticoids the body produces – exerting almost unbelievable effects in certain pro-inflammatory cell lines.

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SKU: 19773956515

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Kelli
Alexandria, US
★★★★★ 5
Works well, good scent
Love the scent and also love that I can let my 7 year old use it to help with chores
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Reviewed in the United States on April 24, 2026
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TM
Grantham, US
★★★★★ 5
Best scent
My favorite Meyer’s scent. Loved that it was on sale too!
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Reviewed in the United States on June 8, 2026
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Alexandria
Dallas, US
★★★★★ 5
Amazing
I love this smells and i love how well it cleans. I have at least one more refill left in my bottle and it has lasted me at least 3 months ! Definitely will buy again. Honestly all of their products are wonderful.
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Reviewed in the United States on May 24, 2026
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Emma Mullet
Whiting, US
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This soap smells amazing!!
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Reviewed in the United States on June 6, 2026
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Kirsche
Battle Creek, US
★★★★★ 4
Not sure it's pure Batana oil
I'm not a botanical expert, so I may be totally wrong about this, but based on the ingredients, I don't think this is pure Batana Oil. The ingredient list (typos included) reads: "Elaeis Oleifera Kernel Oil, Babassuamide DEA, AscorbicAcid, Phytosterols, Carotenoids, Vitamins c." The last 4 ingredients might just be components of the oil itself, rather than additives. But Elaeis Oleifera (American Palm) Kernel Oil is Batana oil. But Babassuamide DEA is an oil that comes from the kernels of the babassu palm, not the American palm. Sure, it's still "palm kernel oil", but if I wanted just any ol' palm kernel oil, then I'd use some out of the cooking oil bottle in the kitchen and save myself a buck. I wanted 100% Pure Batana oil. I also can't figure out why the description talks about it containing Vitamin E, when that isn't listed as an ingredient. If it's been added, then it definitely needs to be listed on the package. If it's a natural chemical part of the oil itself, and the same is true of the Vitamin C listed, then why not list both separately? Or is the Vitamin C listed because it's been added despite them saying it's pure Batana oil? I don't know. So if you just want some kind of palm kernel oil to moisturize your hair, and you're not particular about whether or not it's really pure Batana oil, then this might be the oil for you. But, if you're a stickler for purity, maybe not. And there are lots of cheaper Batana-type palm oils out there that aren't true Batana, if price is more important to you than purity.
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Reviewed in the United States on May 19, 2026

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